⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661665 | 1.00 | — | — | |
| SCHEMBL21228677 | 0.79 | — | — | |
| SCHEMBL14096885 | 0.74 | — | — | |
| SCHEMBL13494685 | 0.74 | — | — | |
| SCHEMBL9075732 | 0.72 | — | — | |
| SCHEMBL12583133 | 0.72 | — | — | |
| SCHEMBL12583505 | 0.72 | — | — | |
| SCHEMBL17481740 | 0.70 | — | — | |
| SCHEMBL6940632 | 0.70 | — | — | |
| SCHEMBL17308706 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192510-A1 | β-CATENIN ANTIBODIES | ENTRADA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20210403459-A1 | SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF | Karyopharm Therapeutics Inc. | 2021-12-30 | — | — | US | disclosed |