Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1686364 | 0.94 | TRPV1 (0.55) | TRPV1 | |
| SCHEMBL1686282 | 0.89 | TRPV1 (0.69) | TRPV1 | |
| SCHEMBL1686463 | 0.81 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL1686559 | 0.81 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL2419321 | 0.81 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL2450012 | 0.80 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL1686352 | 0.80 | TRPV1 (0.63) | TRPV1 | |
| SCHEMBL1686273 | 0.80 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL1686272 | 0.80 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL1686353 | 0.80 | TRPV1 (0.63) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185530-B1 | 5-PHENYL-ISOXAZOLE-3-CARBOXAMIDE DERIVATIVES AS TRPV1 MODULATORS | ORGANON NV (NL) | 2011-09-14 | — | — | EP | claimed |
| EP-2185530-B1 | 5-PHENYL-ISOXAZOLE-3-CARBOXAMIDE DERIVATIVES AS TRPV1 MODULATORS | ORGANON NV (NL) | 2011-09-14 | — | — | EP | disclosed |