Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6765361 | 0.81 | — | — | |
| SCHEMBL12544684 | 0.81 | — | — | |
| SCHEMBL22281529 | 0.78 | TSHR (0.55) | TSHRALDH1A1HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL22329036 | 0.77 | TSHR (0.46) | TSHRALDH1A1THRBHSD17B10CYP2D6 | |
| Hydrochloric Acid SCHEMBL28986509 | 0.76 | TSHR (0.52) | TSHRALDH1A1THRBTP53HIF1A | |
| Hydrochloric Acid SCHEMBL31087897 | 0.76 | TSHR (0.52) | TSHRALDH1A1THRBTP53HIF1A | |
| SCHEMBL8850371 | 0.73 | TSHR (0.79) | TSHRALDH1A1THRBTP53HIF1A | |
| SCHEMBL4945997 | 0.73 | TSHR (0.79) | TSHRALDH1A1THRBTP53HIF1A | |
| SCHEMBL5685352 | 0.73 | TSHR (0.79) | TSHRALDH1A1THRBTP53HIF1A | |
| SCHEMBL8850772 | 0.73 | TSHR (0.79) | TSHRALDH1A1THRBTP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262826-A2 | 1'-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2021-12-30 | — | — | WO | disclosed |