Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25808078 | 1.00 | PTPN11 (0.41) | PTPN11 | |
| SCHEMBL24151101 | 0.90 | PTPN11 (0.53) | PTPN11 | |
| SCHEMBL25808080 | 0.90 | PTPN11 (0.53) | PTPN11 | |
| SCHEMBL24152310 | 0.90 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL25801421 | 0.89 | PTPN11 (0.45) | PTPN11 | |
| SCHEMBL24151065 | 0.89 | PTPN11 (0.47) | PTPN11 | |
| SCHEMBL24151857 | 0.88 | PTPN11 (0.46) | PTPN11 | |
| SCHEMBL24152611 | 0.86 | PTPN11 (0.36) | PTPN11 | |
| SCHEMBL24151112 | 0.85 | PTPN11 (0.36) | PTPN11 | |
| SCHEMBL24151796 | 0.84 | PTPN11 (0.36) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4169913-A1 | SUBSTITUTED PYRAZINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-2021259077-A1 | SUBSTITUTED PYRAZINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-12-30 | — | — | WO | disclosed |