Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25801371 | 0.89 | PTPN11 (0.49) | PTPN11 | |
| SCHEMBL24151354 | 0.89 | PTPN11 (0.42) | PTPN11 | |
| SCHEMBL24152574 | 0.87 | PTPN11 (0.43) | PTPN11 | |
| SCHEMBL24151919 | 0.87 | PTPN11 (0.55) | PTPN11 | |
| SCHEMBL24152328 | 0.85 | PTPN11 (0.43) | PTPN11 | |
| SCHEMBL24151025 | 0.83 | PTPN11 (0.42) | PTPN11 | |
| SCHEMBL25807539 | 0.83 | PTPN11 (0.44) | PTPN11 | |
| SCHEMBL24151883 | 0.83 | PTPN11 (0.46) | PTPN11 | |
| SCHEMBL24151074 | 0.81 | PTPN11 (0.44) | PTPN11 | |
| SCHEMBL24152556 | 0.80 | PTPN11 (0.44) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021259077-A1 | SUBSTITUTED PYRAZINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-12-30 | — | — | WO | disclosed |