Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.78 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.78 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.78 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.72 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.72 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.72 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.72 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.72 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.72 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.72 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20012370 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL13337745 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL19457969 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL11057932 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL23240818 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL19313986 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL23710532 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL23781673 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL22415771 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 | |
| SCHEMBL15106578 | 1.00 | GPBAR1 (0.78) | GPBAR1NR1H4PDE3ATBXA2RSLC10A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021258723-A1 | METHOD FOR SYNTHESIZING LITHOCHOLIC ACID WITH BA AS RAW MATERIAL | 江苏佳尔科药业集团股份有限公司 | 2021-12-30 | — | — | WO | disclosed |