Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 17/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420094 | 0.91 | S1PR1 (0.54) | S1PR1S1PR3KCNH2MAOBMAOA | |
| SCHEMBL1602190 | 0.86 | S1PR1 (0.71) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1602087 | 0.81 | S1PR1 (0.61) | S1PR1S1PR3KCNH2 | |
| SCHEMBL3706281 | 0.80 | S1PR1 (0.52) | S1PR1S1PR3KCNH2MAOBMAOA | |
| SCHEMBL1601626 | 0.79 | S1PR1 (0.61) | S1PR1S1PR3KCNH2MAOB | |
| SCHEMBL1601723 | 0.77 | S1PR1 (0.73) | S1PR1S1PR3KCNH2 | |
| SCHEMBL12269426 | 0.76 | S1PR1 (0.74) | S1PR1S1PR3KCNH2 | |
| SCHEMBL1602358 | 0.76 | S1PR1 (0.74) | S1PR1S1PR3KCNH2 | |
| SCHEMBL2412108 | 0.74 | S1PR1 (0.50) | S1PR1S1PR3KCNH2MAOB | |
| SCHEMBL12269470 | 0.72 | S1PR1 (0.62) | S1PR1S1PR3KCNH2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364976-A1 | S1P receptor modulating compounds and use thereof | EPIX Pharmaceuticals, Inc. (US) | 2011-09-14 | — | — | EP | disclosed |