Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24156083 | 1.00 | GRM5 (0.36) | GRM5POLB | |
| SCHEMBL27083572 | 1.00 | GRM5 (0.36) | GRM5POLB | |
| SCHEMBL24156665 | 0.86 | TSHR (0.35) | POLB | |
| SCHEMBL24156700 | 0.86 | GRM5 (0.40) | GRM5 | |
| SCHEMBL27083547 | 0.86 | GRM5 (0.40) | GRM5 | |
| SCHEMBL24156699 | 0.86 | GRM5 (0.40) | GRM5 | |
| SCHEMBL24156648 | 0.78 | NPC1 (0.41) | POLB | |
| SCHEMBL24156716 | 0.76 | POLB (0.44) | POLB | |
| SCHEMBL24156618 | 0.74 | GRM5 (0.37) | GRM5 | |
| SCHEMBL24156399 | 0.74 | GRM5 (0.37) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021259208-A1 | TYK-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-12-30 | — | — | WO | disclosed |