Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.34 |
| ▸ | CDC25B | P30305 | 6/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.31 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
| ▸ | GJB2 | P29033 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666866 | 0.89 | PDE2A (0.38) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL12393377 | 0.86 | PTPN1 (0.36) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL29113115 | 0.86 | PDE2A (0.39) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL18636484 | 0.86 | PDE2A (0.39) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL24058130 | 0.84 | PDE2A (0.39) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL18636427 | 0.84 | PDE2A (0.39) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL25826686 | 0.82 | PDE2A (0.36) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL24158032 | 0.82 | PDE2A (0.38) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL22646505 | 0.82 | PDE2A (0.38) | PDE2APTPN1CDC25BHSPA5HTR1A | |
| SCHEMBL31063739 | 0.81 | PDE2A (0.37) | PDE2APTPN1CDC25BHSPA5HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3785717-B1 | METHODS FOR TREATING CORONAVIRIDAE INFECTIONS | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |