Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412029 | 0.82 | KDM4E (0.33) | HRH4KDM4EMAPK1 | |
| SCHEMBL2416070 | 0.81 | KDM4E (0.32) | HRH4KDM4EMAPK1 | |
| SCHEMBL2415787 | 0.79 | GAA (0.38) | KDM4EMAPK1 | |
| SCHEMBL2412012 | 0.76 | CCNT1 (0.32) | — | |
| SCHEMBL2411482 | 0.74 | HRH4 (0.39) | HRH4KDM4EMAPK1 | |
| SCHEMBL2411501 | 0.73 | CCNT1 (0.34) | — | |
| SCHEMBL2412757 | 0.72 | GAA (0.38) | — | |
| SCHEMBL2411035 | 0.72 | HRH4 (0.46) | HRH4KDM4EMAPK1 | |
| SCHEMBL2411628 | 0.72 | SCN9A (0.31) | — | |
| SCHEMBL2416112 | 0.72 | CYP1A2 (0.34) | HRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | claimed |