Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | CDC25B | P30305 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18788242 | 1.00 | PDE2A (0.34) | PDE2APTPN1CDC25BTACR2BCHE | |
| SCHEMBL18788247 | 0.91 | PDE2A (0.35) | PDE2APTPN1CDC25BBCHEHTR1A | |
| SCHEMBL15289762 | 0.84 | — | — | |
| SCHEMBL13648927 | 0.84 | PDE2A (0.34) | PDE2APTPN1CDC25BBCHEHTR1A | |
| SCHEMBL23773046 | 0.83 | PDE4D (0.31) | PDE2A | |
| SCHEMBL13667496 | 0.83 | PTPN1 (0.34) | PDE2APTPN1CDC25BBCHEHTR1A | |
| SCHEMBL24557910 | 0.81 | PDE2A (0.34) | PDE2APTPN1CDC25BBCHEHTR1A | |
| SCHEMBL20404007 | 0.81 | PDE2A (0.32) | PDE2A | |
| SCHEMBL18788241 | 0.80 | PDE2A (0.42) | PDE2APTPN1CDC25BTACR2BCHE | |
| SCHEMBL19292338 | 0.80 | PDE2A (0.32) | PDE2APTPN1CDC25BBCHEHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932931-A1 | A NEBULIZER COMPRISING A PHARMACEUTICAL COMPOSITION COMPRISING 2'- SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | Gilead Sciences, Inc. (US) | 2022-01-05 | — | — | EP | disclosed |