Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410080 | 0.87 | SMPD3 (0.40) | PDE10A | |
| SCHEMBL2415328 | 0.85 | HRH4 (0.40) | MAP4K4PDE10A | |
| SCHEMBL2410491 | 0.84 | SMPD3 (0.33) | PDE10A | |
| SCHEMBL2411521 | 0.84 | MAPT (0.39) | MAP4K4HSD11B1 | |
| SCHEMBL2415961 | 0.83 | CHUK (0.39) | PDE10AFPR2 | |
| SCHEMBL2411529 | 0.83 | SMPD3 (0.33) | — | |
| SCHEMBL2416308 | 0.82 | AKT1 (0.39) | MAP4K4FPR1FPR2 | |
| SCHEMBL2414864 | 0.81 | CHUK (0.39) | PDE10A | |
| SCHEMBL2413886 | 0.80 | PDE10A (0.34) | PDE10A | |
| SCHEMBL2415245 | 0.79 | SMPD3 (0.36) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-B1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | OREAL (FR) | 2011-09-21 | — | — | EP | claimed |