Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19153148 | 0.76 | MAPT (0.30) | — | |
| SCHEMBL17868694 | 0.60 | SOS1 (0.45) | HCAR2KMT2A | |
| SCHEMBL24728233 | 0.60 | HCAR2 (0.36) | HCAR2KMT2ATSHR | |
| SCHEMBL19413424 | 0.57 | MAPT (0.35) | HCAR2KMT2ATSHR | |
| SCHEMBL14648769 | 0.56 | HCAR2 (0.70) | HCAR2KMT2ATSHR | |
| SCHEMBL21764920 | 0.56 | HCAR2 (0.70) | HCAR2KMT2ATSHR | |
| SCHEMBL19153868 | 0.55 | — | — | |
| SCHEMBL1007395 | 0.53 | HCAR2 (0.64) | HCAR2KMT2ATSHR | |
| SCHEMBL24877853 | 0.53 | HCAR2 (0.64) | HCAR2KMT2ATSHR | |
| SCHEMBL13778215 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505519-B1 | PYRIDINAMINE-SUBSTITUTED HETEROTRICYCLO COMPOUNDS, PREPARATION THEREOF, AND USE IN MEDICINES | SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN) | 2022-01-05 | — | — | EP | disclosed |