Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MDH1 | P40925 | 1/20 | 0.48 |
| ▸ | MDH2 | P40926 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266977 | 0.84 | TP53 (0.69) | KMT2AMAPTPOLBHPGDNPSR1 | |
| SCHEMBL28649485 | 0.84 | MAPT (0.57) | KMT2AMEN1MAPTPOLBCYP2C9 | |
| SCHEMBL17512399 | 0.83 | KDM4E (0.71) | KMT2AMEN1MAPTPOLBRAB9A | |
| SCHEMBL4253087 | 0.83 | KDM4E (0.70) | KMT2AMEN1MAPTRAB9AHPGD | |
| SCHEMBL10748020 | 0.83 | MAPT (0.59) | KMT2AMEN1MAPTPOLBRAB9A | |
| SCHEMBL13425100 | 0.81 | MAPT (0.58) | KMT2AMEN1MAPTPOLBCYP2C9 | |
| SCHEMBL1554272 | 0.81 | MAPT (0.54) | KMT2AMEN1MAPTPOLBCYP2C9 | |
| SCHEMBL7240818 | 0.81 | MAPT (0.54) | KMT2AMEN1MAPTPOLBCYP2C9 | |
| SCHEMBL14338700 | 0.81 | MAPT (0.68) | KMT2AMEN1MAPTPOLBHPGD | |
| SCHEMBL3044520 | 0.80 | MAPT (0.56) | KMT2AMEN1MAPTPOLBCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022003712-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-01-06 | — | — | WO | disclosed |