Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656791 | 0.90 | TNF (0.57) | TNFP2RX3LMNAGAARAB9A | |
| SCHEMBL24166094 | 0.90 | TNF (0.57) | TNFP2RX3LMNAGAARAB9A | |
| SCHEMBL30656849 | 0.84 | TNF (0.61) | TNFP2RX3LMNAGAARAB9A | |
| SCHEMBL24165915 | 0.84 | TNF (0.61) | TNFP2RX3LMNAGAARAB9A | |
| SCHEMBL30656806 | 0.81 | TNF (0.65) | TNFP2RX3LMNAGAARAB9A | |
| SCHEMBL24165897 | 0.81 | TNF (0.65) | TNFP2RX3LMNAGAARAB9A | |
| SCHEMBL30656858 | 0.79 | TNF (0.65) | TNFP2RX3LMNAGAARAB9A | |
| SCHEMBL24166489 | 0.79 | TNF (0.65) | TNFP2RX3LMNAGAARAB9A | |
| SCHEMBL24166075 | 0.77 | TNF (0.69) | TNFP2RX3LMNARAB9AMAPT | |
| SCHEMBL30656837 | 0.77 | TNF (0.69) | TNFP2RX3LMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022003712-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-01-06 | — | — | WO | disclosed |