⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1034321 | 0.67 | — | — | |
| SCHEMBL9723942 | 0.67 | — | — | |
| SCHEMBL19432260 | 0.61 | KMT2A (0.32) | — | |
| SCHEMBL2407921 | 0.61 | — | — | |
| SCHEMBL22295567 | 0.61 | — | — | |
| SCHEMBL21855039 | 0.61 | — | — | |
| SCHEMBL9507062 | 0.59 | — | — | |
| SCHEMBL6747041 | 0.57 | — | — | |
| SCHEMBL2639 | 0.56 | — | — | |
| SCHEMBL9419190 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539348-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS -LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | Dmitrienko, Gary Igor (CA) | 2013-01-02 | — | — | EP | claimed |
| US-20120329770-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS BETA-LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | DMITRIENKO GARY IGOR (CA) | 2012-12-27 | — | — | US | claimed |
| WO-2011103686-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS β-LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | VISWANATHA , SUNDARAMMA (CA) | 2011-09-01 | — | — | WO | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-0136721-B1 | Carboxyalkenamidocephalosporins | SHIONOGI & CO (JP) | 1993-12-29 | — | — | EP | claimed |
| US-4839352-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1989-06-13 | — | — | US | claimed |
| US-4748170-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1988-05-31 | — | — | US | claimed |
| EP-0252473-A2 | 7 Beta-(substituted) amino-3-substituted cephalosporanic acids and esters | AMERICAN CYANAMID COMPANY (US) | 1988-01-13 | — | — | EP | claimed |
| US-4634697-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1987-01-06 | — | — | US | claimed |
| EP-2539348-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS -LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | Dmitrienko, Gary Igor (CA) | 2013-01-02 | — | — | EP | disclosed |
| US-20120329770-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS BETA-LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | DMITRIENKO GARY IGOR (CA) | 2012-12-27 | — | — | US | disclosed |
| WO-2011103686-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS β-LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | VISWANATHA , SUNDARAMMA (CA) | 2011-09-01 | — | — | WO | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| EP-0552817-B1 | Milbemycin ether derivatives, their preparation and their therapeutic and agrochemical uses | SANKYO CO (JP) | 1998-05-27 | — | — | EP | disclosed |
| US-4194047-A | Substituted N-methylene derivatives of thienamycin | MERCK & CO., INC. (US) | 1980-03-18 | — | — | US | disclosed |
| US-4172144-A | Schiff's base derivatives of thienamycin | MERCK & CO., INC. (US) | 1979-10-23 | — | — | US | disclosed |
| EP-0002210-A1 | 6- and 6,6- disubstituted-2-substituted-pen-2-em-3-carboxylic acids; processes for their preparation and pharmaceutical compositions containing such compounds | MERCK & CO. INC. (US) | 1979-06-13 | — | — | EP | disclosed |
| US-4150145-A | ANTIBIOTIC, BACTERICIDES | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| EP-0001264-A1 | Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation | MERCK & CO. INC. (US) | 1979-04-04 | — | — | EP | disclosed |
| US-4071682-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1978-01-31 | — | — | US | disclosed |