⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3556724 | 0.71 | — | — | |
| SCHEMBL289904 | 0.70 | — | — | |
| SCHEMBL12811807 | 0.66 | — | — | |
| SCHEMBL945668 | 0.66 | — | — | |
| SCHEMBL16050431 | 0.65 | — | — | |
| SCHEMBL1226592 | 0.65 | — | — | |
| SCHEMBL16911777 | 0.62 | — | — | |
| SCHEMBL16061357 | 0.61 | — | — | |
| SCHEMBL16059913 | 0.61 | — | — | |
| SCHEMBL3339047 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395242-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2021-12-23 | — | — | US | claimed |
| EP-3843853-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2021-07-07 | — | — | EP | claimed |
| WO-2020043880-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2020-03-05 | — | — | WO | claimed |
| CN-112654608-B | Fused ring compound having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2024-05-07 | — | — | CN | disclosed |
| US-20210395242-A1 | HETEROCYCLIC COMPOUNDS AS AHR MODULATORS | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2021-12-23 | — | — | US | disclosed |
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |
| EP-1945630-B1 | PYRAZINE DERIVATIVES AS SODIUM CHANNEL MODULATORS FOR THE TREATMENT OF PAIN | PFIZER LTD (GB) | 2011-09-21 | — | — | EP | disclosed |
| US-7572797-B2 | Amino substituted pyrazine derivatives for the treatment of pain | PFIZER INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-20070105872-A1 | N-[6-amino-5-(2,3-dichlorophenyl)pyrazin-2-yl]-3-methylisoxazole-4-carboxamide; N-[6-amino-5-(2,3-dichloro-5-methoxyphenyl)pyrazin-2-yl]-1-methyl-1H-pyrazole-5-carboxamide | PFIZER LIMITED | 2007-05-10 | — | — | US | disclosed |