Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2423340 | 0.94 | BRAF (0.41) | MAPK11MAPK14LMNACHRNA7BRAF | |
| SCHEMBL2423094 | 0.94 | MAPK11 (0.50) | MAPK11MAPK14CHRNA7KDM4EALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL2420295 | 0.88 | MAPK11 (0.45) | MAPK11MAPK14CHRNA7BRAFKDM4E | |
| SCHEMBL2421213 | 0.82 | KMT2A (0.44) | LMNAKDM4EALDH1A1MAPTBRD4 | |
| SCHEMBL2421631 | 0.81 | CHRNA7 (0.41) | CHRNA7BRD4WNT1DYRK1A | |
| SCHEMBL2419695 | 0.80 | SMN1; SMN2 (0.48) | LMNAKDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL223823 | 0.79 | HRH3 (0.38) | MAPK14ALDH1A1BRD4RAB9A | |
| Cyclohexane SCHEMBL2428515 | 0.79 | HRH3 (0.40) | NPC1RAB9A | |
| SCHEMBL2422227 | 0.77 | GRM5 (0.40) | CHRNA7 | |
| SCHEMBL223649 | 0.76 | KCNH2 (0.46) | ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-B1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2011-09-21 | — | — | EP | disclosed |