Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.44 |
| ▸ | JAK3 | P52333 | 20/20 | 0.44 |
| ▸ | JAK1 | P23458 | 16/20 | 0.44 |
| ▸ | JAK2 | O60674 | 15/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30340351 | 1.00 | TYK2 (0.44) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24175068 | 0.87 | TYK2 (0.42) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24175542 | 0.87 | JAK3 (0.56) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL30340362 | 0.87 | JAK3 (0.56) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24170331 | 0.87 | JAK3 (0.56) | TYK2JAK3JAK1JAK2P2RX3 | |
| Trifluoroacetic Acid SCHEMBL28978706 | 0.86 | JAK3 (0.54) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL30340315 | 0.86 | TYK2 (0.45) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24170321 | 0.86 | TYK2 (0.45) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL24170322 | 0.86 | TYK2 (0.47) | TYK2JAK3JAK1JAK2P2RX3 | |
| SCHEMBL30340402 | 0.86 | TYK2 (0.47) | TYK2JAK3JAK1JAK2P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916747-A | Fused heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2022002118-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2022-01-06 | — | — | WO | disclosed |