⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28171841 | 0.71 | — | — | |
| SCHEMBL7560953 | 0.67 | — | — | |
| SCHEMBL7545482 | 0.67 | SLC6A2 (0.33) | — | |
| SCHEMBL17185581 | 0.63 | — | — | |
| SCHEMBL11484936 | 0.63 | — | — | |
| SCHEMBL10808421 | 0.63 | — | — | |
| SCHEMBL28992347 | 0.63 | — | — | |
| SCHEMBL1060395 | 0.62 | — | — | |
| SCHEMBL323173 | 0.62 | — | — | |
| SCHEMBL1120297 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110585165-B | Abuse resistant capsules | R·P·谢勒技术有限公司 | 2022-08-12 | — | — | CN | claimed |
| CN-110585165-A | Abuse resistant capsules | R·P·谢勒技术有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-1119685-A | Amination of rayon | HOECHST AG (DE) | 1996-04-03 | — | — | CN | claimed |
| CN-110585165-B | Abuse resistant capsules | R·P·谢勒技术有限公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| CN-108713061-B | Nucleic acid oligomer for RNA hybridization | 学校法人东京理科大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-110585165-A | Abuse resistant capsules | R·P·谢勒技术有限公司 | 2019-12-20 | — | — | CN | disclosed |
| EP-3131896-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2019-01-30 | — | — | EP | disclosed |
| US-9969724-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2018-05-15 | — | — | US | disclosed |
| US-9808445-B2 | Factor IXa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20170129880-A1 | FACTOR IXa INHIBITORS | MERCK SHARP & DOHME LLC | 2017-05-11 | — | — | US | disclosed |
| US-20110237458-A1 | DRUG DISCOVERY METHOD | Keddem Bioscience Ltd. (IL) | 2011-09-29 | — | — | US | disclosed |
| US-8019550-B2 | Drug discovery method | Keddem Bioscience Ltd. (IL) | 2011-09-13 | — | — | US | disclosed |
| EP-1540329-A4 | DRUG DISCOVERY METHOD | KEDDEM BIO SCIENCE LTD (IL) | 2009-06-10 | — | — | EP | disclosed |
| US-20050277117-A1 | Drug discovery method | KEDDEM BIO-SCIENCE LTD. (IL) | 2005-12-15 | — | — | US | disclosed |
| CN-1229364-C | Intermediates and methods for semi-synthesis of paclitaxel and analogs thereof | INDENA SPA (IT) | 2005-11-30 | — | — | CN | disclosed |
| EP-1540329-A1 | DRUG DISCOVERY METHOD | KEDDEM BIO-SCIENCE LTD. (IL) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004010136-A1 | DRUG DISCOVERY METHOD | KEDDEM BIO-SCIENCE LTD. (IL) | 2004-01-29 | — | — | WO | disclosed |
| CN-1119685-A | Amination of rayon | HOECHST AG (DE) | 1996-04-03 | — | — | CN | disclosed |
| CN-1118825-A | Process for dyeing aminated cellulose/polyester blend fabric with fiber-reactive disperse dyestuffs | HOECHST AG (DE) | 1996-03-20 | — | — | CN | disclosed |