SCHEMBL24196471

SCHEMBL24196471

Cn1c(C#N)ccc(Br)c1=O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 9/20 0.41
PGR P06401 12/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24799594 0.78 AR (0.44) ARPGR
SCHEMBL17603123 0.76 AR (0.41) ARPGR
SCHEMBL17603190 0.76 AR (0.47) ARPGR
SCHEMBL2002285 0.75 AR (0.54) ARPGR
SCHEMBL2114603 0.70 HPGD (0.33)
SCHEMBL3991637 0.68 CRBN (0.31)
SCHEMBL5158088 0.67
SCHEMBL2955486 0.67
SCHEMBL17610033 0.67 MEN1 (0.41) ARPGR
SCHEMBL91095 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022011274-A1 SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 GOLDFINCH BIO, INC. (US) 2022-01-13 WO disclosed