Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240852 | 1.00 | ESR2 (0.50) | ESR2BRD4TYMPMMP3MMP8 | |
| SCHEMBL5733 | 1.00 | — | — | |
| SCHEMBL899402 | 0.90 | ESR2 (0.45) | ESR2BRD4 | |
| SCHEMBL760537 | 0.90 | ESR2 (0.45) | ESR2BRD4TYMP | |
| SCHEMBL15842184 | 0.90 | ESR2 (0.53) | ESR2BRD4TYMP | |
| SCHEMBL21110513 | 0.90 | ESR2 (0.45) | ESR2BRD4TYMP | |
| SCHEMBL103167 | 0.87 | ESR2 (0.43) | ESR2BRD4 | |
| SCHEMBL18421585 | 0.87 | ESR2 (0.43) | ESR2BRD4 | |
| SCHEMBL25025914 | 0.87 | ESR2 (0.43) | ESR2BRD4 | |
| SCHEMBL19837778 | 0.87 | ESR2 (0.43) | ESR2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022011211-A1 | DEOXYNOJIRIMYCIN DERIVATIVES AS GLUCOSIDASE INHIBITORS | EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. (US) | 2022-01-13 | — | — | WO | disclosed |