SCHEMBL2419783

SCHEMBL2419783

COOc1ccccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA12 O43570 1/20 0.46
CA4 P22748 1/20 0.46
CA14 Q9ULX7 1/20 0.46
ACHE P22303 1/20 0.45
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
ALOX15 P16050 1/20 0.40
KDM4E B2RXH2 1/20 0.39
CYP1A2 P05177 1/20 0.39
AOC2 O75106 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL27817768 0.97 TSHR (0.45) TSHRMEN1NPC1RAB9AKMT2A
SCHEMBL22878 0.86 TSHR (0.53) TSHRMEN1NPC1RAB9AKMT2A
SCHEMBL29349760 0.86 TSHR (0.53) TSHRMEN1NPC1RAB9AKMT2A
Hydrogen Peroxide SCHEMBL28159758 0.81 TSHR (0.48) TSHRMEN1NPC1RAB9AKMT2A
SCHEMBL29355560 0.78
SCHEMBL82813 0.78
SCHEMBL10001542 0.77 TSHR (0.45) TSHRMEN1NPC1RAB9AKMT2A
SCHEMBL13647022 0.77 TSHR (0.45) TSHRMEN1NPC1RAB9AKMT2A
SCHEMBL10530264 0.77 TSHR (0.45) TSHRMEN1NPC1RAB9AKMT2A
SCHEMBL28359989 0.76 CA1 (0.72) TSHRKMT2ASMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021100059-A1 PROCESS FOR PREPARING CHROMAN COMPOUNDS LUPIN LIMITED (IN) 2021-05-27 WO disclosed
CN-102803429-B For the refrigerant of high temperature heat transfer 阿克马法国公司 2018-05-25 CN disclosed
US-20130066116-A1 METHOD FOR THE DEPOLYMERIZATION OF LIGNOCELLULOSIC BIOMASS INSTITUT TECHNOLOGIQUE FCBA (FR) 2013-03-14 US disclosed
EP-2547716-A1 METHOD FOR THE DEPOLYMERISATION OF LIGNOCELLULOSIC BIOMASS Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2013-01-23 EP disclosed
WO-2011114058-A1 METHOD FOR THE DEPOLYMERISATION OF LIGNOCELLULOSIC BIOMASS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2011-09-22 WO disclosed
CN-101044244-B Isocyclomaltooligosaccharide, isocyclomaltooligosaccharide synthase, and production method and use thereof HAYASHIBARA BIOCHEM LAB 2010-05-05 CN disclosed
CN-100549062-C Inhibiting catalytically active impurities in polycarbonate prepared by melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2009-10-14 CN disclosed
US-20080312264-A1 Process for the production of an abuse-proofed solid dosage form GRUNENTHAL GMBH (DE) 2008-12-18 US disclosed
CN-101044244-A Isocyclomaltooligosaccharide, isocyclomaltooligosaccharide synthase, and production method and use thereof HAYASHIBARA BIOCHEM LAB (JP) 2007-09-26 CN disclosed
CN-1715306-A Inhibiting catalytically active impurities in polycarbonate prepared by melt transesterification process BAYER MATERIALSCIENCE AG (DE) 2006-01-04 CN disclosed