Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.54 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633780 | 1.00 | MDM2 (0.54) | MDM2MDM4TP53ALDH1A1CASP3 | |
| SCHEMBL22454846 | 1.00 | MDM2 (0.54) | MDM2MDM4TP53ALDH1A1CASP3 | |
| SCHEMBL22444788 | 0.93 | MDM2 (0.63) | MDM2MDM4TP53ALDH1A1CASP3 | |
| SCHEMBL22444972 | 0.93 | MDM2 (0.63) | MDM2MDM4TP53ALDH1A1CASP3 | |
| SCHEMBL28741589 | 0.91 | MDM2 (0.51) | MDM2MDM4TP53 | |
| SCHEMBL26989065 | 0.89 | KMT2A (0.46) | MDM2MDM4TP53CASP3KMT2A | |
| SCHEMBL8106707 | 0.89 | MDM2 (0.54) | MDM2MDM4TP53CASP3KMT2A | |
| SCHEMBL12052763 | 0.89 | MDM2 (0.54) | MDM2MDM4TP53CASP3KMT2A | |
| SCHEMBL29400972 | 0.84 | MDM2 (0.60) | MDM2MDM4TP53ALDH1A1CASP3 | |
| SCHEMBL2310132 | 0.84 | MDM2 (0.60) | MDM2MDM4TP53ALDH1A1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939962-A1 | METHOD FOR PREPARING AROMATIC AMINO ACID DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-01-19 | — | — | EP | disclosed |
| CN-113692401-A | Process for producing aromatic amino acid derivative | 中外制药株式会社 | 2021-11-23 | — | — | CN | disclosed |