Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 3/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30145424 | 0.69 | CYP1A2 (0.47) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL17138519 | 0.69 | CYP1A2 (0.47) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL17138522 | 0.69 | CYP1A2 (0.47) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL17138848 | 0.69 | CYP1A2 (0.47) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL30145435 | 0.69 | CYP1A2 (0.47) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL29868746 | 0.69 | CYP1A2 (0.64) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL151036 | 0.69 | CYP1A2 (0.64) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL16447389 | 0.68 | CYP1A2 (0.45) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL16587300 | 0.68 | CYP11B1 (0.53) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 | |
| SCHEMBL9768532 | 0.68 | CYP1A2 (0.70) | CYP1A2CYP2C19BACE1KDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939971-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | Synchronicity Pharma, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |