SCHEMBL24201630

SCHEMBL24201630

Cc1ncnc(Cl)cnc(C)s1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.38
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2669058 0.70
Ammonia Solution, Strong SCHEMBL27803897 0.69
SCHEMBL933680 0.64
SCHEMBL119227 0.64
SCHEMBL10442596 0.64 HCAR2 (0.46) HCAR2
SCHEMBL755027 0.62
SCHEMBL14345626 0.62
SCHEMBL30338589 0.62
SCHEMBL9942642 0.62
SCHEMBL899250 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3939981-A1 FUSED THIAZOLOPYRIMIDINE DERIVATIVES AS MNKS INHIBITORS LifeArc (GB) 2022-01-19 EP disclosed