Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2423231 | 0.89 | KMT2A (0.55) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL2422541 | 0.88 | KMT2A (0.56) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL3479819 | 0.86 | KMT2A (0.47) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL2423174 | 0.86 | KMT2A (0.59) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL2420432 | 0.85 | KMT2A (0.53) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL6431623 | 0.85 | KMT2A (0.55) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL2427569 | 0.85 | KMT2A (0.52) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL2427448 | 0.85 | KMT2A (0.52) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL2421511 | 0.85 | KMT2A (0.53) | KMT2AMEN1PKMALDH1A1LMNA | |
| SCHEMBL2429271 | 0.84 | KMT2A (0.53) | KMT2AMEN1PKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012995-B1 | Pharmaceutically active sulfonamide derivatives | MERCK SERONO SA (CH) | 2011-09-06 | — | — | US | disclosed |