Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26035325 | 1.00 | TSHR (0.46) | TSHRHTTTDP1POLBAPEX1 | |
| SCHEMBL28294394 | 0.83 | TSHR (0.51) | TSHRHTTTDP1POLBAPEX1 | |
| SCHEMBL26035322 | 0.82 | TSHR (0.47) | TSHRHTTTDP1CYP2C9KMT2A | |
| SCHEMBL28004958 | 0.81 | TSHR (0.49) | TSHRHTTTDP1POLBAPEX1 | |
| SCHEMBL24205261 | 0.79 | TSHR (0.44) | TSHRHTTTDP1POLBAPEX1 | |
| SCHEMBL16694191 | 0.78 | TSHR (0.59) | TSHRHTTTDP1POLBAPEX1 | |
| SCHEMBL16694184 | 0.78 | TSHR (0.59) | TSHRHTTTDP1POLBAPEX1 | |
| SCHEMBL26034665 | 0.78 | TK2 (0.53) | TSHRHTTTDP1POLBAPEX1 | |
| SCHEMBL26034607 | 0.78 | TK2 (0.53) | TSHRHTTTDP1POLBAPEX1 | |
| SCHEMBL26035299 | 0.78 | TK2 (0.53) | TSHRHTTTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022012798-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2022-01-20 | — | — | WO | disclosed |