Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896496 | 0.84 | HTT (0.33) | MAPTHTTRECQL | |
| SCHEMBL15109950 | 0.82 | PIK3CA (0.32) | MAPTCASP1 | |
| SCHEMBL9761039 | 0.79 | MAPT (0.34) | KMT2AMAPTHTTRECQLCASP1 | |
| SCHEMBL24214731 | 0.75 | KMT2A (0.31) | KMT2AMAPT | |
| SCHEMBL24215325 | 0.69 | MAPT (0.50) | KMT2AMAPT | |
| SCHEMBL15233567 | 0.69 | CCR4 (0.38) | KMT2AMAPTHTTRECQLCASP1 | |
| SCHEMBL21616710 | 0.68 | CD274 (0.38) | — | |
| SCHEMBL609085 | 0.67 | CCR4 (0.45) | — | |
| SCHEMBL13256727 | 0.67 | KMT2A (0.36) | KMT2AMAPTHTTRECQLCASP1 | |
| SCHEMBL30505760 | 0.67 | CCR4 (0.39) | KMT2AMAPTHTTRECQLCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022015624-A1 | SUBSTITUTED DIHYDROPYRAZINEDIONES AS MODULATORS OF THE NMDA RECEPTOR | SCHRÖDINGER, INC. (US) | 2022-01-20 | — | — | WO | disclosed |