Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TPO | P07202 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24215056 | 1.00 | CA1 (0.45) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL7631267 | 0.86 | TSHR (0.41) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL18391961 | 0.83 | CA1 (0.46) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL2878217 | 0.83 | CA1 (0.46) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL1663117 | 0.83 | CA1 (0.46) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL1663119 | 0.83 | CA1 (0.46) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL1664059 | 0.83 | CA1 (0.46) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL1975300 | 0.79 | CA1 (0.46) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL1975297 | 0.79 | CA1 (0.46) | CA1CA2CA7CA9TDP1 | |
| SCHEMBL2882825 | 0.79 | TDP1 (0.45) | CA1CA2CA7CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022016195-A1 | PROCESSES FOR THE PREPARATION OF ARGINASE INHIBITORS AND THEIR SYNTHETIC INTERMEDIATES | INCYTE CORPORATION (US) | 2022-01-20 | — | — | WO | disclosed |