Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 18/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409818 | 1.00 | HDAC6 (0.41) | HDAC6EPHB4KDRTEK | |
| SCHEMBL30409760 | 0.89 | HDAC6 (0.39) | HDAC6 | |
| SCHEMBL25355716 | 0.89 | HDAC6 (0.40) | HDAC6EPHB4KDRTEK | |
| SCHEMBL25349538 | 0.88 | HDAC6 (0.40) | HDAC6EPHB4KDRTEK | |
| SCHEMBL30410488 | 0.87 | HDAC6 (0.41) | HDAC6EPHB4KDRTEK | |
| SCHEMBL30408165 | 0.86 | HDAC6 (0.41) | HDAC6 | |
| SCHEMBL30408447 | 0.85 | HDAC6 (0.43) | HDAC6EPHB4KDRTEK | |
| SCHEMBL24216245 | 0.84 | HDAC6 (0.41) | HDAC6EPHB4 | |
| SCHEMBL30409217 | 0.84 | HDAC6 (0.41) | HDAC6EPHB4 | |
| SCHEMBL24216208 | 0.81 | HDAC6 (0.41) | HDAC6EPHB4KDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022013728-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2022-01-20 | — | — | WO | disclosed |