Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555102 | 1.00 | KMT2A (0.56) | KMT2ANPC1MEN1KDM4EMAPT | |
| SCHEMBL22793229 | 0.92 | HDAC1 (0.59) | KMT2ANPC1MEN1KDM4EMAPT | |
| SCHEMBL18874959 | 0.87 | NPC1 (0.58) | KMT2ANPC1MEN1KDM4EMAPT | |
| SCHEMBL10103983 | 0.84 | NPC1 (0.55) | KMT2ANPC1MEN1KDM4EMAPT | |
| SCHEMBL19939430 | 0.84 | HDAC1 (0.62) | KMT2ANPC1MEN1KDM4EMAPT | |
| SCHEMBL13104839 | 0.83 | HDAC1 (0.63) | KMT2ANPC1MEN1KDM4EMAPT | |
| SCHEMBL8161491 | 0.82 | HDAC1 (0.65) | KMT2ANPC1MEN1KDM4EMAPT | |
| SCHEMBL18874948 | 0.82 | HDAC1 (0.54) | KMT2ANPC1MEN1KDM4EMAPT | |
| SCHEMBL16127281 | 0.82 | HDAC1 (0.68) | KMT2AKDM4EHDAC1HDAC6HDAC10 | |
| SCHEMBL12531524 | 0.82 | KMT2A (0.49) | KMT2ANPC1MEN1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220025254-A1 | Complexes and Ligands | THE GENERAL HOSPITAL CORPORATION | 2022-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220025254-A1 | Complexes and Ligands | BID, CLTB, NECTIN4 | KMT2A 4577/4885NPC1 657/4885MEN1 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.