Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.59 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24601730 | 0.93 | FOLH1 (0.70) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24601548 | 0.93 | FOLH1 (0.70) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24601734 | 0.93 | FOLH1 (0.70) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24601803 | 0.91 | FOLH1 (0.67) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24274183 | 0.88 | F2 (0.73) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL8115912 | 0.86 | FOLH1 (0.61) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL16602282 | 0.86 | F2 (0.71) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL23126030 | 0.86 | F2 (0.68) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL16421337 | 0.86 | F2 (0.73) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL16602280 | 0.86 | F2 (0.73) | FOLH1PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220026420-A1 | MOLECULES AND METHODS FOR IMPROVED IMMUNODETECTION OF SMALL MOLECULES SUCH AS HISTAMINE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-01-27 | — | — | US | disclosed |