Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 7/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20339036 | 0.90 | PAICS (0.42) | PAICSKCNH2HDAC3HDAC2 | |
| SCHEMBL24220430 | 0.89 | PIM1 (0.44) | PAICSNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20340330 | 0.89 | PAICS (0.45) | PAICSKCNH2HDAC3HDAC2CYP1A2 | |
| SCHEMBL24220398 | 0.88 | PAICS (0.61) | PAICSKCNH2HDAC3HDAC2 | |
| SCHEMBL20339057 | 0.88 | PAICS (0.53) | PAICSKCNH2HDAC3HDAC2 | |
| SCHEMBL20352112 | 0.86 | PAICS (0.49) | PAICSKCNH2HDAC3HDAC2CYP1A2 | |
| SCHEMBL20352048 | 0.86 | PAICS (0.40) | PAICSKCNH2HDAC3HDAC2CYP1A2 | |
| SCHEMBL21571648 | 0.86 | PAICS (0.42) | PAICSKCNH2HDAC3HDAC2CYP1A2 | |
| SCHEMBL20352125 | 0.85 | BACE1 (0.48) | TSHRSMN1; SMN2 | |
| SCHEMBL20352073 | 0.84 | PAICS (0.41) | PAICSKCNH2HDAC3HDAC2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562824-B1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2022-01-26 | — | — | EP | disclosed |