Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.52 |
| ▸ | MTOR | P42345 | 17/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.50 |
| ▸ | ATR | Q13535 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21851063 | 0.88 | ATM (0.51) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL21851097 | 0.87 | ATM (0.56) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL21851215 | 0.86 | ATM (0.53) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL21851127 | 0.86 | ATM (0.57) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL21851164 | 0.86 | ATM (0.54) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL23615854 | 0.85 | ATM (0.57) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL21851043 | 0.84 | ATM (0.58) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL21851066 | 0.83 | ATM (0.51) | ATMMTORPIK3CAATRKCNH2 | |
| SCHEMBL29968726 | 0.82 | ATM (0.53) | ATMMTORPIK3CAATRPRKDC | |
| SCHEMBL21851099 | 0.81 | ATM (0.56) | ATMMTORPIK3CAATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11230549-B2 | Quinolino-pyrrolidin-2-one derivative and application thereof | MEDSHINE DISCOVERY INC. (CN) | 2022-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11230549-B2 | Quinolino-pyrrolidin-2-one derivative and application thereof | ATM, CHEK2, CHEK1 | ATM 1/4885MTOR 274/4885PIK3CA 870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.