SCHEMBL24222016

SCHEMBL24222016

O=C(NC12CC3CC(CC(C3)C1)C2)c1nn(CCCCF)c2ccccc12

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.81
CNR1 P21554 9/20 0.81
HDAC1 Q13547 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HTR3A P46098 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31052991 1.00 CNR2 (0.81) CNR2CNR1HDAC1HDAC6HTR3A
SCHEMBL17297543 0.99 CNR2 (0.80) CNR2CNR1HDAC1HDAC6
SCHEMBL13502771 0.90 CNR2 (0.81) CNR2CNR1HDAC1HDAC6
SCHEMBL16755272 0.90 CNR2 (1.00) CNR2CNR1
SCHEMBL29359055 0.90 CNR2 (1.00) CNR2CNR1
SCHEMBL13502770 0.90 CNR2 (0.81) CNR2CNR1HDAC1HDAC6
SCHEMBL17388191 0.89 CNR2 (0.81) CNR2CNR1HDAC1HDAC6
SCHEMBL29019200 0.89 CNR2 (0.80) CNR2CNR1HDAC1HDAC6
SCHEMBL17388587 0.88 CNR2 (0.79) CNR2CNR1HDAC1HDAC6
SCHEMBL13502769 0.87 CNR2 (0.77) CNR2CNR1HDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220026380-A1 NUCLEAR MAGNETIC RESONANCE IMPLEMENTED SYNTHETIC INDOLE AND INDAZOLE CANNABINOID DETECTION, IDENTIFICATION, AND QUANTIFICATION HOFSTRA UNIVERSITY (US) 2022-01-27 US disclosed