Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24223681 | 0.82 | PARP1 (0.47) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL14413122 | 0.74 | HPGD (0.50) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL29343549 | 0.74 | TDP1 (0.47) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL11787753 | 0.74 | PARP1 (0.52) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL11787750 | 0.74 | PARP1 (0.52) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL28425343 | 0.74 | PARP1 (0.53) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL29085641 | 0.74 | PARP1 (0.53) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL16960884 | 0.72 | HPGD (0.52) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL10143068 | 0.72 | PARP1 (0.54) | HPGDTDP1PARP1HDAC8HDAC6 | |
| SCHEMBL23714922 | 0.71 | PARP1 (0.42) | HPGDTDP1PARP1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3942934-A1 | MCT4 INHIBITORS FOR TREATING DISEASE | Vettore, LLC (US) | 2022-01-26 | — | — | EP | disclosed |