SCHEMBL2422355

SCHEMBL2422355

O=C(Cl)C=CC12CCN(CC1)CC2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2422354 1.00
Hydrochloric Acid SCHEMBL2423055 0.98
Hydrochloric Acid SCHEMBL2423056 0.98
SCHEMBL2416168 0.80 TSHR (0.35)
Hydrochloric Acid SCHEMBL2419237 0.78 TSHR (0.33)
Hydrochloric Acid SCHEMBL2419238 0.78 TSHR (0.33)
SCHEMBL204562 0.64
SCHEMBL592281 0.64 KCNH2 (0.31)
SCHEMBL2421100 0.63
Hydrochloric Acid SCHEMBL2425335 0.62 KCNH2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1930330-B1 Pleuromutilin derivatives as antimicrobials SMITHKLINE BEECHAM LTD (GB) 2011-09-21 EP disclosed