Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 18/20 | 0.65 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.52 |
| ▸ | FGFR2 | P21802 | 7/20 | 0.52 |
| ▸ | FGFR3 | P22607 | 7/20 | 0.52 |
| ▸ | EGFR | P00533 | 5/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.52 |
| ▸ | FYN | P06241 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | EPHB3 | P54753 | 2/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | PRKACG | P22612 | 1/20 | 0.47 |
| ▸ | PRKACB | P22694 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23653204 | 0.88 | FGFR4 (0.84) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16133982 | 0.83 | FGFR4 (0.91) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24224969 | 0.81 | FGFR4 (0.76) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24225057 | 0.80 | FGFR4 (0.84) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16137315 | 0.79 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL16133996 | 0.78 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16133993 | 0.77 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16133994 | 0.77 | FGFR4 (0.82) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653016 | 0.76 | FGFR4 (0.69) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL23653040 | 0.76 | FGFR4 (0.73) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943087-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2022-01-26 | — | — | EP | disclosed |