Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.56 |
| ▸ | EGFR | P00533 | 5/20 | 0.54 |
| ▸ | WEE1 | P30291 | 7/20 | 0.51 |
| ▸ | FGFR2 | P21802 | 6/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071618 | 0.86 | FGFR1 (0.59) | FGFR1EGFRWEE1FGFR2FGFR4 | |
| SCHEMBL16071529 | 0.86 | FGFR1 (0.57) | FGFR1EGFRWEE1FGFR2FGFR4 | |
| SCHEMBL16071789 | 0.82 | FGFR1 (0.61) | FGFR1EGFRWEE1FGFR2FGFR4 | |
| SCHEMBL16071534 | 0.81 | FGFR1 (0.61) | FGFR1EGFRWEE1FGFR2FGFR4 | |
| SCHEMBL15413093 | 0.80 | FGFR1 (0.72) | FGFR1EGFRWEE1FGFR4SRC | |
| SCHEMBL16072110 | 0.78 | FGFR1 (0.53) | FGFR1EGFRWEE1FGFR2FGFR4 | |
| SCHEMBL16071536 | 0.77 | FGFR1 (0.62) | FGFR1EGFRWEE1FGFR2FGFR4 | |
| SCHEMBL20384688 | 0.77 | FGFR1 (0.67) | FGFR1EGFRWEE1FGFR2FGFR4 | |
| SCHEMBL24224923 | 0.77 | FGFR1 (0.65) | FGFR1EGFRWEE1FGFR2FGFR4 | |
| SCHEMBL16071530 | 0.77 | FGFR1 (0.54) | FGFR1EGFRWEE1FGFR2FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3943087-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | Celgene CAR LLC (BM) | 2022-01-26 | — | — | EP | disclosed |