Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1S | Q13698 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29373482 | 1.00 | CACNA1S (0.43) | CACNA1STP53THRBSMN1; SMN2PTGS1 | |
| Hydrochloric Acid SCHEMBL29370572 | 0.99 | CACNA1S (0.42) | CACNA1STP53THRBSMN1; SMN2PTGS1 | |
| SCHEMBL24228679 | 0.89 | CYP3A4 (0.45) | CACNA1STP53THRBSMN1; SMN2PTGS1 | |
| SCHEMBL30445533 | 0.88 | CACNA1S (0.43) | CACNA1STP53THRBSMN1; SMN2PTGS1 | |
| SCHEMBL24228678 | 0.88 | CACNA1S (0.43) | CACNA1STP53THRBSMN1; SMN2PTGS1 | |
| SCHEMBL24228688 | 0.85 | GSK3B (0.35) | TP53SMN1; SMN2GSK3B | |
| SCHEMBL29373153 | 0.85 | GSK3B (0.35) | TP53SMN1; SMN2GSK3B | |
| SCHEMBL24228689 | 0.74 | KDM1A (0.40) | GSK3BGAATSHRALDH1A1MEN1 | |
| SCHEMBL24228687 | 0.72 | GSK3B (0.35) | TP53SMN1; SMN2GSK3BGAA | |
| SCHEMBL30445676 | 0.72 | GSK3B (0.35) | TP53SMN1; SMN2GSK3BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263915-A1 | RADIOLABELED COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2023-08-24 | — | — | US | disclosed |
| US-20230263915-A1 | RADIOLABELED COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2023-08-24 | — | — | US | disclosed |
| CN-116322673-A | Radiolabeled compounds | 伦敦国王学院 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022023439-A1 | RADIOLABELED COMPOUNDS | KING'S COLLEGE LONDON (GB) | 2022-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230263915-A1 | RADIOLABELED COMPOUNDS | TMEM14C, PIGO, SLCO1B1 | CACNA1S 4555/4885TP53 993/4885THRB 1381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.