Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 2/20 | 0.67 |
| ▸ | TK1 | P04183 | 1/20 | 0.54 |
| ▸ | TYMP | P19971 | 4/20 | 0.53 |
| ▸ | PYGM | P11217 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10267691 | 1.00 | TK2 (0.67) | TK2TK1TYMPPYGMALDH1A1 | |
| SCHEMBL28805336 | 0.92 | TK2 (0.69) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL12718535 | 0.92 | TK2 (0.69) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL28805337 | 0.92 | TK2 (0.69) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL4951028 | 0.91 | TK2 (0.63) | TK2TK1TYMPPYGMALDH1A1 | |
| SCHEMBL6512561 | 0.91 | TK2 (0.64) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL5414718 | 0.91 | TK2 (0.64) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL5502493 | 0.91 | TK2 (0.67) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL5502489 | 0.91 | TK2 (0.67) | TK2TYMPPYGMALDH1A1LMNA | |
| SCHEMBL30533444 | 0.91 | TK2 (0.62) | TK2TK1TYMPPYGMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022026387-A9 | HBV BINDING OLIGONUCLEOTIDES AND METHODS OF USE | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-19 | — | — | WO | disclosed |
| WO-2022026387-A1 | HBV BINDING OLIGONUCLEOTIDES AND METHODS OF USE | ALIGOS THERAPEUTICS, INC. (US) | 2022-02-03 | — | — | WO | disclosed |