Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24230498 | 0.91 | ESR2 (0.36) | ESR2 | |
| SCHEMBL8936822 | 0.91 | ESR2 (0.34) | ESR2 | |
| SCHEMBL24230499 | 0.90 | ESR2 (0.37) | ESR2PDE3BPDE3A | |
| SCHEMBL24230479 | 0.88 | AKR1C3 (0.36) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL8938077 | 0.84 | ESR2 (0.32) | ESR2 | |
| SCHEMBL9014846 | 0.84 | ESR2 (0.39) | ESR2 | |
| SCHEMBL8936913 | 0.83 | ESR2 (0.33) | ESR2 | |
| SCHEMBL8936922 | 0.82 | CCNT1 (0.34) | ESR2 | |
| SCHEMBL8936929 | 0.81 | PDE5A (0.32) | ESR2 | |
| SCHEMBL8936843 | 0.81 | ESR2 (0.32) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022136223-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022023400-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2022-02-03 | — | — | WO | disclosed |