Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 14/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16497775 | 0.91 | CACNA1B (0.61) | CACNA1BGAAEPHX2TRPV4 | |
| SCHEMBL16497772 | 0.91 | CACNA1B (0.61) | CACNA1BGAAEPHX2TRPV4 | |
| SCHEMBL66757 | 0.86 | CACNA1B (0.74) | CACNA1BGAAEPHX2 | |
| SCHEMBL2457872 | 0.85 | CACNA1B (0.66) | CACNA1BGAAEPHX2 | |
| SCHEMBL66019 | 0.85 | CACNA1B (0.66) | CACNA1BGAAEPHX2 | |
| SCHEMBL3246463 | 0.85 | CACNA1B (0.66) | CACNA1BGAAEPHX2 | |
| SCHEMBL66747 | 0.84 | CACNA1B (0.74) | CACNA1BGAAEPHX2TRPV4 | |
| SCHEMBL64800 | 0.84 | CACNA1B (0.77) | CACNA1BGAAEPHX2 | |
| SCHEMBL66566 | 0.84 | CACNA1B (0.77) | CACNA1BGAAEPHX2 | |
| SCHEMBL65961 | 0.84 | CACNA1B (0.74) | CACNA1BGAAEPHX2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367790-A2 | SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | Abbott Laboratories (US) | 2011-09-28 | — | — | EP | claimed |