Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326760 | 0.81 | ADA (0.39) | ADAPDE4BADORA2AADORA2B | |
| SCHEMBL14134333 | 0.81 | KDR (0.37) | ADAPDE4B | |
| SCHEMBL21539463 | 0.79 | ADA (0.36) | ADAPDE4B | |
| SCHEMBL21942688 | 0.78 | ADA (0.36) | ADAPDE4BADORA2AADORA2B | |
| SCHEMBL23619282 | 0.76 | ADA (0.32) | ADAPDE4B | |
| SCHEMBL18521610 | 0.71 | GRM2 (0.39) | ADAPDE4BADORA2AADORA2B | |
| SCHEMBL18520808 | 0.69 | TP53 (0.39) | ADAPDE4B | |
| SCHEMBL24239187 | 0.67 | PDE4B (0.33) | ADAPDE4BADORA2AADORA2B | |
| SCHEMBL22326748 | 0.67 | PDE4B (0.33) | ADAPDE4B | |
| SCHEMBL22381518 | 0.66 | ADORA2A (0.31) | PDE4BADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033435-A1 | Cyclic Di-Nucleotide Compounds as STING Agonists | MERCK SHARP & DOHME CORP. (US) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033435-A1 | Cyclic Di-Nucleotide Compounds as STING Agonists | STING1, CGAS, IFNAR1 | ADA 163/4885PDE4B 188/4885ADORA2A 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.