Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.56 |
| ▸ | STING1 | Q86WV6 | 9/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24239238 | 0.94 | NT5E (0.59) | NT5ERNASEL | |
| SCHEMBL18520910 | 0.93 | ADORA1 (0.58) | NT5ERNASEL | |
| SCHEMBL18521232 | 0.93 | ADORA1 (0.58) | NT5ERNASEL | |
| SCHEMBL18521240 | 0.93 | ADORA1 (0.58) | NT5ERNASEL | |
| SCHEMBL18521638 | 0.93 | ADORA1 (0.58) | NT5ERNASEL | |
| SCHEMBL18510965 | 0.93 | ADORA1 (0.58) | NT5ERNASEL | |
| SCHEMBL18521239 | 0.93 | ADORA1 (0.58) | NT5ERNASEL | |
| SCHEMBL18521472 | 0.93 | ADORA1 (0.58) | NT5ERNASEL | |
| SCHEMBL21539347 | 0.93 | ADORA1 (0.58) | NT5ERNASEL | |
| SCHEMBL18520953 | 0.93 | ADORA1 (0.58) | NT5ERNASEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220033435-A1 | Cyclic Di-Nucleotide Compounds as STING Agonists | MERCK SHARP & DOHME CORP. (US) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033435-A1 | Cyclic Di-Nucleotide Compounds as STING Agonists | STING1, CGAS, IFNAR1 | NT5E 1230/4885STING1 1/4885RNASEL 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.