Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP10 | Q14694 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025529 | 0.94 | TDP1 (0.56) | TDP1SIRT6HSPB1HPGDSMN1; SMN2 | |
| SCHEMBL10784720 | 0.92 | TDP1 (0.70) | TDP1SIRT6HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL2724028 | 0.88 | TDP1 (0.62) | TDP1SIRT6HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3512673 | 0.88 | TDP1 (0.62) | TDP1SIRT6HSPB1HPGDSMN1; SMN2 | |
| SCHEMBL10784985 | 0.88 | TDP1 (0.62) | TDP1SIRT6HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL12846984 | 0.87 | TDP1 (0.47) | TDP1SIRT6HSPB1SMN1; SMN2BRAF | |
| SCHEMBL10785510 | 0.86 | TDP1 (0.61) | TDP1SIRT6HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1027039 | 0.86 | TDP1 (0.61) | TDP1SIRT6HPGDSMN1; SMN2BRAF | |
| SCHEMBL17530357 | 0.86 | TDP1 (0.76) | TDP1SIRT6HPGDSMN1; SMN2BRAF | |
| SCHEMBL4851442 | 0.86 | TDP1 (0.65) | TDP1SIRT6HSPB1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117254-A1 | PIPERIDINE AMIDES AS MODULATORS OF THE GHRELIN RECEPTOR | PROSIDION LIMITED (GB) | 2011-09-29 | — | — | WO | disclosed |