Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.35 |
| ▸ | CA2 | P00918 | 10/20 | 0.35 |
| ▸ | CA9 | Q16790 | 8/20 | 0.35 |
| ▸ | CA12 | O43570 | 7/20 | 0.35 |
| ▸ | PPM1D | O15297 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12855832 | 1.00 | CA1 (0.35) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL1934037 | 1.00 | CA1 (0.35) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL12855792 | 1.00 | CA1 (0.35) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL1140405 | 0.90 | CA1 (0.34) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL1140126 | 0.90 | CA1 (0.34) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL1139923 | 0.88 | CA1 (0.36) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL1139948 | 0.86 | PPM1B (0.38) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL1139205 | 0.86 | PPM1D (0.35) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL1140236 | 0.86 | PPM1B (0.38) | CA1CA2CA9CA12PPM1D | |
| SCHEMBL9989942 | 0.84 | PPM1D (0.38) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950692-A1 | NOVEL TRICYCLIC COMPOUNDS | AbbVie Inc. (US) | 2022-02-09 | — | — | EP | disclosed |