Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158699 | 1.00 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4ACACBPPARG | |
| SCHEMBL4161150 | 1.00 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4ACACBPPARG | |
| SCHEMBL11848580 | 0.88 | SLC6A2 (0.50) | SLC6A2SLC6A3SLC6A4ACACBMEN1 | |
| SCHEMBL196800 | 0.87 | TAAR1 (0.48) | SLC6A2SLC6A3LMNATAAR1 | |
| SCHEMBL3940696 | 0.84 | SLC6A2 (0.59) | SLC6A2SLC6A3SLC6A4ACACBPPARG | |
| SCHEMBL19342839 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A3SLC6A4ACACBPPARG | |
| SCHEMBL192679 | 0.82 | SLC6A2 (0.57) | SLC6A2SLC6A3SLC6A4ACACBPPARG | |
| SCHEMBL6642378 | 0.81 | TAAR1 (0.40) | SLC6A2SLC6A3ALDH1A1TAAR1 | |
| SCHEMBL3371824 | 0.81 | ESR1 (0.48) | ACACBIDO1LMNATAAR1 | |
| SCHEMBL2946718 | 0.80 | SLC6A2 (0.55) | SLC6A2SLC6A3SLC6A4ACACBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006013399-A1 | PHARMACEUTICAL INTERMEDIATES AND A PROCESS FOR THE PREPARATION THEREOF | EGIS Gyógyszergyár Rt. (HU) | 2006-02-09 | — | — | WO | claimed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | claimed |
| EP-4429663-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | Vigil Neuroscience, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-117466790-B | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-117466790-A | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-114716296-B | Efficient halogenation synthesis method of alkyl halide | 润药仁智(北京)科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| CN-114716296-A | Efficient halogenation synthesis method of alkyl halide | 北京大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114634432-A | High-efficiency synthesis method of alkyl aryl thioether compound | 北京大学 | 2022-06-17 | — | — | CN | disclosed |
| US-20220144848-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | US | disclosed |
| EP-3898634-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-1999006408-A1 | NEW 2,3-BENZODIAZEPINE DERIVATIVES | Gyógyszerkutató Intézet Kft. (HU) | 1999-02-11 | — | — | WO | disclosed |
| US-5807851-A | MUSCLE RELAXANTS; NERVOUS SYSTEM DISORDERS | EGIS GYOGYSZERGYAR RT. (HU) | 1998-09-15 | — | — | US | disclosed |
| EP-0802195-A2 | Substituted 2,3-benzodiazepine derivatives, process and intermediates for their preparation and pharmaceutical compositions comprising them as well as their use | EGIS GYOGYSZERGYAR RT. (HU) | 1997-10-22 | — | — | EP | disclosed |
| US-4474748-A | ANTIBIOTICS, FUNGICIDES, ANTISEPTICS | JOHNSON & JOHNSON (US) | 1984-10-02 | — | — | US | disclosed |
| US-4321257-A | Potentiated medicaments | JOHNSON & JOHNSON (US) | 1982-03-23 | — | — | US | disclosed |
| US-4197318-A | CYCLOHEXYL SUBSTITUTED ALKANOLS AS POTENTIATORS | JOHNSON & JOHNSON (US) | 1980-04-08 | — | — | US | disclosed |
| US-4091090-A | PENETRANT ACCELERATOR COMPRISING CYCLOHEXYL-SUBSTITUTED ALKANOLS | JOHNSON & JOHNSON (US) | 1978-05-23 | — | — | US | disclosed |
| US-4006218-A | MICROBIOCIDE | JOHNSON & JOHNSON (US) | 1977-02-01 | — | — | US | disclosed |
| US-3991201-A | 1-(β-Aryl-β-R-ethyl)imidazoles as antimicrobial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144848-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | MVD, VASP, SELP | SLC6A2 2774/4885SLC6A3 3643/4885SLC6A4 3804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.