Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.58 |
| ▸ | PHF8 | Q9UPP1 | 14/20 | 0.56 |
| ▸ | KDM5A | P29375 | 2/20 | 0.55 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.55 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17693133 | 0.90 | KDM4C (0.59) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL17604514 | 0.89 | KDM4C (0.73) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL29376754 | 0.89 | KDM4C (0.73) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL17604513 | 0.88 | KDM4C (0.70) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL17604607 | 0.88 | PHF8 (0.71) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL24244169 | 0.87 | PHF8 (0.57) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL17604643 | 0.87 | PHF8 (0.69) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL17604527 | 0.86 | KDM4C (0.72) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL17604539 | 0.85 | KDM4C (0.72) | KDM4CPHF8KDM5AKDM5BKDM2B | |
| SCHEMBL17604609 | 0.84 | PHF8 (0.72) | KDM4CPHF8KDM5AKDM5BKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |